Comprehensive Biomarker Discovery and Validation for by Horvatovich, Peter; Bischoff, Rainer; Thurston, David E;

By Horvatovich, Peter; Bischoff, Rainer; Thurston, David E; Fox, David; Rotella, David

Content material: creation to biomarker discovery and validation; medical context of proteomics biomarker discovery and validation, authority rules; Biomarker discovery: sufferer choice; Biomarker discovery: Experimental layout and biobanking; Biomarker discovery: physique fluids; Biomarker discovery: tissues; Biomarker discovery: mass spectrometry established profiling structures; Biomarker discovery: array dependent profiling systems; Biomarker discovery: information preprocessing for LC-MS information; Biomarker discovery: info preprocessing for Maldi imaging, and 2nd electrophoresis and protein arrays facts; Biomarker discovery: statistical research and validation; Biomarker validation: biomarker validation equipment; practical biomarker validation; scientific program: case reports scientific program: precis and destiny know-how improvement traits

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Epiphanie Medicorum. Speculum videndi urinas hominum. Clavis aperiendi portas pulsuum. Berillus discernendi causas & differentias febrium. Sodalitas Celtica: Nuremberg, 1506. 2. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. , 2001, 69(3), 89–95. 3. M. , BMJ, 2011, 343, d4163. 4. H. Services, Editor. 2011. 5. R. Katz, Biomarkers and surrogate markers: an FDA perspective, NeuroRx, 2004, 1(2), 189–95. 6. H. Services, Editor. 2005. 7. V. J. Swan, C.

Anthony and B. Dunn, The search for the ideal SERM, Expert Opin. , 2002, 3(6), 681–91. 14. K. Dechering, C. Boersma and S. , Curr. Med. , 2000, 7(5), 561–76. 15. V. G. , Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop, Control Clin. Trials, 2001, 22(5), 485–502. 16. J. F. Griffith and H. K. Genant, Bone mass and architecture determination: state of the art, Best Pract. Res. Clin. Endocrinol. , 2008, 22(5), 737–64. 1039/9781849734363-00003 34 Chapter 1 17.

M. , How to improve R&D productivity: the pharmaceutical industry’s grand challenge, Nat. Rev. Drug. , 2010, 9(3), 203–14. 10. I. Kola and J. , Nat. Rev. , 2004, 3(8), 711–5. 11. I. Kola, The state of innovation in drug development, Clin Pharmacol Ther, 2008, 83(2), 227–30. 12. A. J. van Gool, B. Henry and E. D. Sprengers, From biomarker strategies to biomarker activities and back, Drug Discov. , 2010, 15(3-4), 121–6. 13. B. Arun, M. Anthony and B. Dunn, The search for the ideal SERM, Expert Opin.

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Comprehensive Biomarker Discovery and Validation for by Horvatovich, Peter; Bischoff, Rainer; Thurston, David E;
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