By Luciano Martini
The Encyclopedia of Endocrine Diseases is an authoritative reference built by means of sixteen foreign specialists who recruited the world's most sensible scientists for contributions. This stellar reference paintings makes a speciality of approximately 500 endocrine illnesses addressing every little thing from acromeglay, diabetes, high blood pressure, osteoporosis, thyroid sickness, Von Hippel-Lindau disorder, unexplained weight-loss, to androgen comparable issues. This encyclopedia is a vital addition to any library assortment written to be available for either the medical and non-clinical reader.
Associate Editors comprise: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga.
Also to be had on-line through ScienceDirect - that includes broad searching, looking out, and inner cross-referencing among articles within the paintings, plus dynamic linking to magazine articles and summary databases, making navigation versatile and simple. for additional info, pricing strategies and availability stopover at www.info.sciencedirect.com.
* comprises approximately 500 entries addressing all points of endocrine diseases
* greater than 800 eminent researchers contributed from 25 various international locations round the world
* greater than 900 figures and 450 tables displayed
* accomplished thesaurus comprising 1500 definitions
* The Editor-in-Chief is former editor of the magazine Frontiers in Neuroendocrinology and has contributed to over forty books within the box of endocrinology
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In addition, IGF-2 helps the fetal adrenal to synthesize cortisol and androgen by regulating the enzymes p450scc, p450c17, and 3b-hydroxysteroid dehydrogenase. Basic fibroblast growth factor is a mitogenic protein and is more effective (stimulating proliferation) on adrenal cells of the definitive zone than those of the fetal zone. Epidermal growth factor (EGF) and transforming growth factor-a (TGF-a) are growth factors with sequence homology that both activate the EGF receptor. This may lead to hypertrophy of the fetal adrenal.
Adrenal Cortex, Anatomy . Adrenal Cortex, Development . Adrenal Insufficiency . Angiotensin, Evolution of . EGF and Related Growth Factors . Fibroblast Growth Factor (FGF) . Glucocorticoids, Overview . Insulin-like Growth Factors Adrenal Cortex Development, Regulation of Further Reading Challis, J. R. , Matthews, S. , Patel, F. , Moss, T. J. , and Newnham, J. (2001). The fetal placental hypothalamic– pituitary–adrenal (HPA) axis, parturition, and postnatal health. Mol. Cell. Endocrinol. 185, 135–144.
T he Tabulae Anatomicae mention Bartholomeo Eustachius, who apparently first described the anatomy of the adrenal glands in 1563. A central physiologic role for the adrenals was presented in 1849 by Thomas Addison, and today Addison’s disease refers to adrenal insufficiency, a life-threatening condition. To better understand pathophysiologic states of the adrenal glands, one must recall their normal anatomy and physiology. The adrenal glands are divided into cortex and medulla. The adrenal cortex is composed of three zones— the glomerulosa, fasciculata, and reticularis.
