By Boyd L. O'Dell, Roger A. Sunde
Assessing either macro and micro parts, this single-source reference deals entire, definitive info on all the crucial mineral elements–focusing on biochemical and physiological tactics. Describes intimately the functionality of the nutritionally worthwhile components printed during the most modern concepts in molecular biology in addition to conventional learn tools! Furnishing instant entry to hands-on info, the guide of Nutritionally crucial Mineral components covers chemical homes research metabolism metabolic and physiological functionality toxicity destiny study wishes and masses extra! Written by means of greater than 25 across the world famous specialists within the box and containing approximately 3400 bibliographic citations, the instruction manual of Nutritionally crucial Mineral components is an imperative source for nutritionists, biochemists, nutrients scientists and technologists, natural and analytical chemists, dietitians, pharmacologists, toxicologists, physiologists, molecular biologists, public and allied overall healthiness execs, common perform physicians, and upper-level undergraduate and graduate-level scholars in those disciplines.
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Extra info for Handbook of Nutritionally Essential Mineral Elements
Sample text
In deficient guinea pigs the concentration of these electrolytes changes in the same direction as noted in rats except for potassium, which is unchanged from control values (107). There  < previous page < previous page next page > next page > page_130 page_131 Page 131 TABLE 4 Serum/Plasma Electrolyte Changes from Controls in Experimental Magnesium Deficiencya Mg Ca P K Rat ℜ↓ ℜ↑ ℜ↓ ℜ→ Mouse ℜ↓ ℜ↓ℜ→ ℜ↑ Guinea pig ℜ↓ ℜ↓ℜ→ ℜ↑ Chick ℜ↓ ℜ↓ ℜ→ aSee Mg Ca P K Dog ℜ↓ ℜ↓ ℜ↑ ℜ→ Calf ℜ↓ ℜ↓ℜ→ ℜ→ ℜ→ Monkey ℜ↓ ℜ↓ V ℜ→ Human ℜ↓ ℜ↓ V ℜ↓ text for references and variability.
Magnesium and potassium are usually reduced in the cardiac and skeletal muscles of deficient rats with little or no change in liver and kidney, whereas sodium and calcium are elevated on diets with usual amounts of calcium and phosphate (summarized in Ref. 112). Decreased cardiac magnesium 41 42 and potassium have been noted in deficient mice (109). In deficient guinea pigs the concentration of these electrolytes changes in the same direction as noted in rats except for potassium, which is unchanged from control values (107).
An older literature which noted low serum/plasma magnesium values in patients with suspected or proven myocardial infarction suggested that a primary state of magnesium depletion was involved. As noted above, such claims are contradicted by contrary evidence. Furthermore, more recent data indicate that a number of clinical factors affect serum and cardiac magnesium concentrations variably in such patients. These include (a) the time of drawing of blood following onset of chest pain, (b) the degree of pain, (c) the prior and often chronic use of diuretics (which may induce magnesium and potassium depletion), (d) postinfarction lipolysis (also induced by ethanol withdrawal, epinephrine, and surgery) causing increased serum fatty acids which lower serum magnesium, and (e) the extent of the infarction per se.
