By Stephen Gough, Susan Manley, Irene Stratton
Adapting to the IFCC method of reporting HbA1c poses a problem to generations of future health execs who've learnt the proportion approach regarding the foremost medical trials, in sort 1 and sort 2 diabetes, the DCCT and UKPDS. this useful paperback illuminates the transition path.Using real-life case stories to demonstrate genuine medical occasions, the ebook exhibits you ways to exploit mmol/mol devices in day-by-day perform. every one case research indicates the outdated percent devices along the IFCC devices for fast comparability. Produced in organization with Diabetes united kingdom, this pocketbook is helping you're employed with self belief within the IFCC approach.
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Additional info for HbA1c in Diabetes: Case studies using IFCC units
Example text
The main treatment aim was to prevent hypoglycaemia. An education programme was started for all staff within the nursing home. It covered the nature of diabetes and its complications, causes, symptoms of hypoglycaemia and hyperglycaemia and their treatment, and blood glucose monitoring. Follow-up When reviewed one month later, nursing home staff reported that he was now very pleasant and approachable, and was agreeable to interventions since stopping gliclazide. There was no further history of hypoglycaemia.
Information may be not always be available for rarer variant haemoglobins and their effects on specific analytical systems. Affinity chromatography This type of chromatography relies on the differential binding of glycated proteins to a boronate column, rather than on differences in charge. The HbA1c values reported will include any glycated abnormal haemoglobins present as well as normal glycated haemoglobin. However, it is not known if normal and variant haemoglobins bind glucose at the same rate.
Comparison of 11 human insulin assays: implications for clinical investigation and research. Clin Chem 2007;53:922–32. Nathan DM, Kuenne J, Borg R, Zheng H, Schoenfeld D, Heine RJ. Translating the A1c assay into estimated average glucose values. Diabetes Care 2008;31:1473–9. NICE. Management of Blood Glucose. NICE Clinical Guideline G. London: National Institute for Clinical Excellence 2008. uk Rohlfi ng CL, Wiedmeyer H-M, Little RR, England JD, Tennill A, Goldstein DE. Defi ning the relationship between plasma glucose and HbA1c analysis of glucose profi les and HbA1c in the Diabetes Control and Complications Trial.
