By Lawrence D. Robbins
With complete revisions and updates, plus new chapters on herbs and supplements, "triptans," headache in the course of breast feeding, menstrual migraine, opiate abuse, cervicogenic explanations of headache, and workout and sexual headache, this e-book provides a whole and in-depth diversity of data for basic care physicians and neurologists.
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Short term side effects include nausea, insomnia. GI upset, nervousness, and facial flushing. Weight gain or water retention may occur. Fatigue can be a problem, as can agitation. Very rarely, femoral head necrosis has been reported, even with small amounts of steroids. In general, however, steroids are weIl tolerated over the short term. Second-Line Abortive Therapy 33 Narcotics and Sedatives When the usual first line medications do not help, stronger narcotics may be given PO or IM, usually with antinausea medication at the same time.
Again, the tablets are usually mueh better tolerated (and convenient). Occasionally, rebound headaehe will occur with IInitrex, but it is unusual. When the headaehe returns, it is more likely to be reeurrenee, not rebound. Serious Side Effects The two serious side effeets have been myoeardial infaretion and (possibly) stroke. Stroke has oeeurred in several eases, but it is unclear whether this is a random event or due to the Imitrex. Over 13 million people have had Imitrex, and it has been used to treat over 200 million migraines.
In the early studies on this treatment for acute migraine, the Depacon decreased the pain and associated nausea of migraine. The lack of cardiovascular toxicity renders this treatment very appealing. In addition, the fact that Depacon is not addicting, and generally non-sedating, may be extremely helpful for treatment of acute migraine. • ANTIEMETIC MEDICATION If patients have plis or suppositories of antinausea medication on hand, they are often able to avoid an emergency room trip. Most of the antinausea medications are sedating, which is usually feit by migraineurs to be 36 2.
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