By Stylianos Nicolaidis
Redux™ is a innovative new anti-obesity drug that has simply been licensed (July 1996) via the FDA. it's the first weight administration drug therapy to be introduced within the usa in two decades and isn't addictive, in contrast to previous medicinal drugs used for this function. weight problems administration and Redux™ incorporates a short advent which leads as much as its discovery and comprises an summary of recent developments in weight problems administration. The ebook lists the pharmacological profile of the drug, given by means of specialists all in favour of tracking the consequences of the drug at the mind neurotransmitters, in addition to detailing the consequences (including security info) of some of the medical trials. Key gains* Covers all facets of a progressive new drug* Lists pharmacological profile of the drug* contains security info* initiatives destiny traits in weight administration
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Relatively weak satiety signals. The pattern of eating is largely influenced by processes occurring during consumption (satiation) and those which follow eating (post-ingestive satiety). , 1994). g. , 1985), they appear to be weaker than other nutrient-induced signals, at Dexfenfluramine: Biological Regulator of Risk Factors for Overeating 25 least in some vulnerable individuals. , 1995). In this further way dietary fat constitutes a risk factor for overconsumption. Palatability and sensory features of foods.
1978, 1992). , 1988). Dexfenfluramine therefore increases serotonergie transmission both indirectly, by inhibiting 5-HT uptake and enhancing its release, and directly, by its metabolite's action on 5-HTzc receptors. This makes it difficult to assess the contribution of presynaptic mechanisms in dF-indueed hypophagia, which depend on the animal species and the route of administration. p. , 1991). , 1995) do not reduce the anorectic effect of dF, since activation of 5-HT2c receptors by dNF could prevail.
This has become more of a problem in recent years owing to the tendency to view neurotoxicological effects as an extension of the pharmacological effects of the chemical or drug in question.
