By P. Deetjen, J.W. Boylan, K. Kramer, R.V. Coxon
This little e-book was once assembled from the authors' lectures to clinical scholars and was once initially released as one quantity within the sequence Human body structure, edited via O. H. Gauer, ok. Kramer, and R. Jung. The editors meant that every quantity during this sequence be self sufficient of the others and we have now stored to this goal. we've incorporated right here basically fabric that we believe is critical for scientific scholars to grasp with a purpose to comprehend kidney functionality in healthiness and, via later extrapolation, in ailment. The contents leisure on authorized rules estab lished via experiments, and little area is given to what's debatable, hypo thetical, or unresolved. we're happy that Dr. Coxon has been stimulated to arrange an English language model of this article. we are hoping that it'll function a prepared reference and overview resource for the beleaguered clinical pupil. P. Deetjen J. W. Boylan K.
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Extra resources for Physiology of the Kidney and of Water Balance
Sample text
KRAMER sodium and an accompanying passive movement of chloride creates an osmotically driven flux of water, some additional quantities ofNa + and Clwould be drawn out of the tubular lumen passively. When allowance is made for this solvent drag effect, the ratio of sodium actively transported to oxygen used is somewhat reduced. Ultrastructure of the Nephron In conformity with their large energy turnover, the cells of the proximal convoluted tubule exhibit a high degree of morphological differentiation.
From Fig. 7 meq of sodium are transported. Considering that a small part of the oxygen consumed will be needed for the reabsorption and secretion of other substances, the 02/Na may approach I: 8. This ratio for renal tissue exceeds that found in any other actively transporting cell. For example, in nerve the ratio of oxygen used to sodium transported is I: I, while in submaxillary gland it is I: 2 and in pancreas it is I: 3. " In the tubule, reflection coefficients (see page 46) for sodium chloride exist that are significantly less than I (l08).
Considering that a small part of the oxygen consumed will be needed for the reabsorption and secretion of other substances, the 02/Na may approach I: 8. This ratio for renal tissue exceeds that found in any other actively transporting cell. For example, in nerve the ratio of oxygen used to sodium transported is I: I, while in submaxillary gland it is I: 2 and in pancreas it is I: 3. " In the tubule, reflection coefficients (see page 46) for sodium chloride exist that are significantly less than I (l08).
