By M.D. David Wheatley
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I get tired more easily than I used to. I get tired from doing anything. I get too tired to do anything. 0 1 2 3 ITEM R. My appetite is no worse than usual. My appetite is not as good as it used to be. My appetite is much worse now. I have no appetite at all any more. ITEM 0 1 2 3 s. I haven't lost much weight, if any, lately. I have lost more than 5 pounds. I have lost more than 10 pounds. I have lost more than 15 pounds. 0 1 2 3 ITEM T. I am no more concerned about my health than usual. I am concerned about aches and pains, or upset stomach, or constipation, or other unpleasant feelings in my body.
It is very rare in general practice to see cases of pure anxiety or pure depression, and so with these minor modifications, these rating scales can be used for both types of case. Since the grades of severity are defined in each case, these do not rely upon the individual investigator's own interpretations of severity. B. ) (c) Hamilton Depression Scale Of the many scales that are available for assessing depressive and other symptoms, the system developed by Professor Max Hamilton of Leeds14 has the advantage of being relatively short (21 items in the original scale), easy to administer, and is widely accepted amongst research workers and clinicians in this field.
If in fact, they cannot be made alike (as for instance in the comparison between a liquid preparation and a tablet preparation), then a double-blind placebo technique can be employed. There are several occasions, when this may be required as follows: (a) Comparison of two different dose forms This would apply to a comparison between a capsule and a tablet, a liquid and a tablet, an injection and a tablet, a suppository and oral medication, etc. The frequency of dosage must be the same for the two preparations, and then all that is required is the preparation of two sets of placebos.
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