By A. Gholamrezanezhad
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Extra resources for Stem Cells in Clinic and Research
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For others, the differentiation potency of hUC-MSCs into neural lineage has attracted extensive attention. The pioneering study in the neuronal induction of hUC-MSCs was accomplished by Mitchell et al. , 2011). In another experiment, hUC-MSCs began to express neuron-specific proteins and exhibit retraction of cell body, elaboration of processes, and clustering of cells after three days’ induction with neuronal conditioned medium (NCM). , 2004). Using a three-step neural induction protocol 60% of the neuroglial cells transformed from hUC-MSCs were stained positive for microtubuleassociated protein (MAP-2) and 32% stained positive for GFAP.
Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease. Journal of Gastroenterology Volume 44, Number 3, 167-172. Sekine S, Gutierrez PJ, & Yu-Ang LB, et al. (2007). Liverspecific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology, 45:361-8, 2007. Stem Cells: General Features and Characteristics 19 Shafritz DA, Oertel M, & Menthena A, et al. (2006). Liver stem cells and prospects for liver reconstitution by transplanted cells.
Gastroenterology, 111:1654–60, 1996. Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang TH, & Nephew KP. (2008). Identification and characterization of ovarian cancer-initiating cells from primary human tumors, Cancer research 68 (11): 4311–20. Zulewski H, Abraham Ej Gerlach MJ, Daniel PB, Moritz W, Muller B, Vallejo M, Thomas MK, & Habener JF. (2001). Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiated ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes.
