By Hans Brunner
Hypertension experts and different physicians must be conversant in the newest examine and effects from scientific trials to make sure sufferers obtain the simplest care attainable. during this ebook Professor Brunner has introduced jointly a crew of well-known specialists to check the giant output of peer-reviewed literature during this box. Readers will locate insightful studies of greater than a hundred key papers released long ago yr, highlighting vital findings and discussing the course that destiny learn must take to respond to these concerns nonetheless unresolved.
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Extra resources for The Year in Hypertension
Sample text
Hypertension 2000; 35: 1025–30. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA 1991; 265: 3255–64. This page intentionally left blank 3 Long-term management of antihypertensive therapy in general practice MICHEL BURNIER, SARA TADDEI, CAROLINE RHÉAUME Introduction If hypertension is well controlled, target organ damage can be prevented and, in the long term, the likelihood of coronary disease, heart failure, stroke and premature death can be reduced.
To achieve these aims successfully, studies are performed in selected groups of patients and comparisons are made with other drugs which are likely to be inferior. Efficacy of drugs in lowering blood pressure The most recent major drug class to be studied is angiotensin type 1 receptor blockers (ARBs). Data from placebo-controlled studies or studies comparing the effect of a drug with that of another drug claim a response rate of up to 80 or 90% and achievement of control in up to 50% or more patients ͉5–10͉.
35. 36. 37. predicts outcome in the Second Australian National Blood Pressure Study (ANBP2). J Hypertens 2004; 22(Suppl 2): S12. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Gattobigio R, Guerrieri M, Comparato E, Benemio G, Porcellati C. Altered circadian blood pressure profile and prognosis. Blood Press Monit 1997; 2: 347–52. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensinconverting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.
